Researchers show that loss of the SPRTN enzyme lets DNA–protein crosslinks accumulate, leak DNA into the cytoplasm, activate ...

A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most powerful genetic "on switches" in cancer cells, called super-enhancers, drive ...

In a quiet lab at Utrecht University, researchers have built a tool that lets you watch one of life’s most serious crises unfold in real time. Inside every cell, DNA breaks, repairs, and sometimes ...

Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...

DNA is often described as the instruction manual for building the fundamental components of life. Proteins are helpers that ...

A new fluorescent sensor is giving scientists an unprecedented view of how cells respond to DNA damage, capturing the repair process as it unfolds in real time. The tool, developed at Utrecht ...

New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human ...

Whenever cells divide, there is a high risk of damage to the genetic material. After all, the cell has to duplicate its entire genetic material and copy billions of genetic letters before it divides.

As people age, their immune systems deteriorate. This makes them more susceptible to infections and can mean that vaccines ...

February marks Cancer Prevention Month. Research shows lifestyle change and early detection can make a big difference in ...

If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by ...