Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a double-strand break involves the severing of both strands of the DNA double ...

Genome instability can cause numerous diseases. Cells have effective DNA repair mechanisms at their disposal. A research team has now gained new insights into the DNA damage response. Whenever cells ...

Cedars-Sinai scientists have created a new experimental drug called TY1 that helps the body repair damaged DNA and restore injured tissue. The discovery came from studying tiny molecular messages ...

TY1 has the structure of existing RNA drugs, and works like its natural version – amplifying the activity of the Trex1 gene, which increases the activity of immune cells that rally around damaged DNA ...

Sunburn has traditionally been attributed to UV-induced DNA damage. However, a new study by the University of Copenhagen and Nanyang Technological University, Singapore, reveals that RNA, another ...

Cedars-Sinai scientists have developed an experimental drug that repairs DNA and serves as a prototype for a new class of medications that fix tissue damage caused by heart attack, inflammatory ...

Insights could not only pave the way for new treatment strategies for genetic disorders, cancer and neurodegenerative diseases, but also enhance gene-editing technologies.

Francesca Storici consults at Tessera Therapeutics. She has received funding from the National Institutes of Health and the National Science Foundation. Your DNA is continually damaged by sources both ...

(The Conversation is an independent and nonprofit source of news, analysis and commentary from academic experts.) Francesca Storici, Georgia Institute of Technology (THE CONVERSATION) Your DNA is ...