An MRI-based cohort study shows HLA-B27–positive axial spondyloarthritis is linked to higher inflammation and distinct clinical features.

There is no specific “diagnostic” or pathognomonic laboratory marker for ankylosing spondylitis/axial spondyloarthritis (AS/axSpA), and diagnosis is based on clinical history, physical examination and ...

Axial disease is common and burdensome in patients with psoriatic arthritis (PsA). Human leukocyte antigen-B27 (HLA-B27) is a risk factor for axial PsA; treatment response by HLA-B27 status is ...

The HLA-B27 genetic marker is known to be associated with increased risk for various arthropathies, including JIA. Whether the genetic marker's presence has prognostic value has been uncertain. In ...