Thiopurines are frequently used for the treatment of IBD. The complex pharmacology, metabolism, mechanism of action and toxicity profile of these immunosuppressive drugs have now been partly ...
The development of novel anticancer agents targeting DNA replication and repair mechanisms remains a priority in leukemia therapy. In this study, newly synthesized derivatives incorporating bis-indole ...
A topical cream activated the skin's immune defenses and suppressed tumor growth in two preclinical models of cutaneous ...
Some 110 million U.S. households use a range–or cooktop and oven–for cooking. About two-thirds of those are powered by electricity, while one-third use natural gas or other fuels. But of the ...
Researchers have discovered a previously unknown signalling cascade that determines how powerful our innate immune system responds to virus infections. This discovery has broad implications for ...
The complexities of drug development for rare diseases, including small patient populations, phenotypic variability, and the high costs associated with large-scale clinical trials, have long hindered ...
Eleuthero (Eleutherococcus senticosus) is a traditional Asian medicinal plant with preclinical anti-inflammatory, ...
Enzymes catalyze nearly all of the chemical reactions that occur in biological systems. Enzymes are generally proteins but also include catalytic DNA and catalytic RNA. As effective biological ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results